026152 REDA S M, AL-GHANNAM S M, EL-RAHMAN S N A (Chemistry Dep, Imam Abdulrahman Bin Faisal Univ, P.O. Box 1982, Dammam 31441, Saudi Arabia, Email: email@example.com) : Effect of source of silica on properties of Fe2O3/SiO2 nanocompsites and their application on hepatic injury in rats as adsorbents for removal of heavy metal from drinking water. Asian J Chem 2018, 30(3), 625-32.
A series of iron oxide silica composites (70/30, 50/50 and 30/70) were prepared using rice hull silica gel as natural silica and TEOS. The prepared samples were characterized by X-ray diffraction, FTIR spectra, BET measurement and SEM. The results show that the particle size is dependent synthesis conditions. BET measurement showed that the values of surface area of the samples are on the range of (320-43 m2/g) and increase with increasing the iron content. The results showed that the surface area of composites prepared from nature silica is lower than that prepared from TEOS. This result was explained on the basis of particle size effect. SEM showed that the size and homogeneity of particles are independent on the Fe2O3 content. Additionally, the effect of drinking water heavy metals (DWHM: Pb, Hg, Ni, Fe and Mg) and DWHM purified with nature silica and TEOS (0.05 and 1.0 g/L.W) on liver injury was evaluated in male rats, as manifested by changes in the activities of certain serum enzymes, such as Fasting blood sugar (FBS), TC, LDL-C, HDL-C, TG, ALT and AST were determined as markers of liver disease. In addition, ALP, g-glutamyltransferase (GGT), LDH and CK were also determined in male rats. The results showed significantly (p £ 0.05) deceased in serum TC, TG, LDL, AST, ALT, ALP, FBS and LDH in male rats administration of DWHM purified with nature silica and TEOS (0.05 and 1.0 g/L.W) compared to rats administration of DWHM (PC). On the other hand, HDL and CK were increased significantly (p £ 0.05) compared to PC. All these results were accompanied by histological observations in liver. The results demonstrate that nature silica has a beneficial effect in DWHM purification than TEOS.
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